Type 2 diabetes mellitus (T2DM) is closely associated with the risk of developing cardiovascular complications.A new Electric Tools approach to treatment of T2DM, based on the inhibition of the sodium-glucose cotransporter type 2 (SGLT2) ensures reliable insulin-independent glycemic control with quick overcome of glucotoxicity, reduction of insulin
Triple-negative breast cancer Mezzalunas (TNBC) patients exhibit variable responses to chemotherapy, suggesting an underlying molecular heterogeneity.In the current study, we analyzed publicly available transcriptome data from 360 TNBC and 88 normal breast tissues, which revealed activation of nucleosome and cell cycle as the hallmarks of TNBC.Mech
Abstract Previously we have generated inducible liver tumor models by transgenic expression of an oncogene and robust tumorigenesis can be rapidly induced by activation of the oncogene in both juvenile and adult fish.In the present study, we aimed at chemical intervention of tumorigenesis for understanding molecular pathways of tumorigenesis and fo
Aid agencies (AAs) provide a range of humanitarian and health related assistance globally.However, the trust placed on them is eroding.Evidence for this includes accusations of a decline in their humanitarianism, and the increasing number of conflicts with host states.An analysis of the concerns expressed yields two possible reasons: a relative lac